Tales from the Open Source Brain kick-off

A contingent from OpenWorm attended the recent Open Source Brain kick-off meeting organized by the Silver Lab (UCL) in Alghero, Sardinia. 

The main goal of the meeting was to launch Open Source Brain (OSB): an awesome resource to share and visualize open neuronal models, created at the SIlver Lab. What makes OSB even more interesting is that in future it will be possible to run web-based neuronal simulations of the available models.

Open Source Brain is dear to our worm hearts for many reasons - first because it wants to promote sharing of open models and, second, because it re-uses Geppetto, the open simulation engine we are building to simulate THE OpenWorm.

An OpenWorm progress report poster was presented at the meeting, with highlights being the NeuroML spatial connectome of C. elegans also available via the OSB visualizer and a progress report on the recent efforts to integrate electrophysiology and fluid mechanics (codename “electrofluid”), first steps to obtain a complete simulation of the C. elegans motor system. 

Besides open collaborative development of neuronal models, the other main theme of the meeting turned out being computational models of the cerebellum. There also was a notable talk from Richard Gerkin who presented neuroUnit - an integrated framework to test neuronal models against experimental data - and as a consequence it was refreshing to hear scientists debate about unit-testing of their models. More of this please. 

In conclusion, this meeting was pretty darn great: great people, great location (just look at the pictures), great food. 

The worms approve!

6opensource, openscience, opensourcebrain, osb, openworm, neuroscience, alghero, sardinia,

Is This Virtual Worm the First Sign of the Singularity? f

Fantastic article covering OpenWorm on The Atlantic!

6press, openworm, openscience,

Building blocks for a digital worm

Five independent muscle compartments demo by Andrey Palyanov, OpenWorm core team member.  

These orange blocks slowly creak to life as digital artificial muscle building blocks of the OpenWorm simulation, the first truly biological digital lifeform.

   More is yet to do but today’s progress is extremely exciting for the OpenWorm community as we can see the model taking shape!

6biology, digital biology, science, neuro,

Neuroscience: Tiny worm sheds light on giant mystery about neurons f

neurosciencestuff:

Scientists have identified a gene that keeps our nerve fibers from clogging up. Researchers in Ken Miller’s laboratory at the Oklahoma Medical Research Foundation (OMRF) found that the unc-16 gene of the roundworm Caenorhabditis elegans encodes a gatekeeper that restricts flow of cellular…

Once again C. elegans to the rescue!

Source: eurekalert.org

6c. elegans, Neuroscience,

Are you ready for some biology horror? An amazing and unsettling video of P. pacificus eating our good pal C. elegans!

Awesome work by Dan Bumbarger

6biology, p.pacificus, c.elegans,

A brief introduction to C. elegans: everything you need to know about C. elegans basic biology in 2 minutes by OpenWorm! :)

Explore the C. elegans anatomy cell-by-cell with the OpenWorm browser!

6C. elegans, science, biology, open-science, open-source, Education,

Scientists at Stanford have come up with a way to make whole brains transparent.

Here’s the original paper and the news article.

6neuroscience, imaging, science,

neurosciencestuff:

Human BRAIN Initiative

Watch it to Believe it. http://www.humanbrainproject.eu/
Full 10 Year Joint EU funding (2013-2023) with over 1 Billion Euro`s has now started!

Source: youtube.com

6neuroscience, human, brain,

OpenWorm Journal Club: Father of the connectome

Meet the father of the original connectome, Dr. John White, first author of the original 1986 C. Elegans connectome paper that launched the connectomics movement!

Get the original paper online here.

6openwrom, openscience, Neuroscience, C. elegans, connectome, johnwhite, journalclub,

Stunning C. elegans Nervous System Fly-Through by Chris Grove, as appeared on the digital version of the March issue of Wired UK in the context of an article about the OpenWorm project.

6openworm, c. elegans, connectome, video, openscience,

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